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Grants and Initiatives

Active Grants

Title:

Conference: BRIDGE: Building Research Initiatives and Developmental Growth for Excellence

Goal:

The goal of the conference is to equip faculty, staff, and administrators from participating institutions with the knowledge and skills necessary to effectively develop and submit competitive proposals to the National Science Foundation, thereby strengthening research excellence and external funding acquisition in Puerto Rico.

Funding:

National Sciences Foundation

Total Cost:

$53,000

Role:

Principal Investigator

Managing entity

Universidad de Puerto Rico at Aguadilla

Period of support:

August 2024-July 2025

Title:

Strengthening Teaching and Advancing Research Partnerships

Goal:

Building a Pipeline of Hispanic Students to Support the STEM Workforce

Funding:

National Sciences Foundation

Total Cost:

$800,000

Role:

Principal Investigator

Managing entity

University of Puerto Rico at Aguadilla

Period of support:

January 2022- December 2027

Title:

Hippocampal astrocytic Kir4.1 channel function in Type 2 diabetic mice: impact on neuronal hyperexcitability.

Goal:

Understand how hyperglycemia affects astrocytic homeostatic functions leading to neuronal hyperexcitability.

Funding:

National institute of Health – National Institute of Neurological Disorders and Stroke

Total Cost:

$364,000

Role:

Principal Investigator

Managing entity

University of Puerto Rico at Aguadilla

Period of support:

January 2022- December 2024

Title:

Alpha-7 receptor-mediateProject Pilot- Facultyd activity of hypothalamic Mc4R neurons in obese mice.

Goal:

Understand the role of Alpha-7 receptor-mediated activity of hypothalamic Mc4R neurons in obese mice.

Funding:

Project Pilot- Faculty

Total Cost:

$18,000

Role:

Co-PI

Managing entity

Universidad Central del Caribe , School of Medicine

Period of support:

February 1, 2024-September 1, 2025

Completed Grants

Title:

The role of neuroinflammation in diabetes-induces neuronal epileptiform activity.

Goal:

Study how diabetic induced neuroinflammation results in neuronal epileptiform activity and provide supplemental funding to support and enhance the training of a post-doctoral fellow in Dr. Méndez-González laboratory and study.

Funding:

National institute of Health – National Institute of Neurological Disorders and Stroke

Total Cost:

$156,000

Role:

Principal Investigator

Managing Entity

University of Puerto Rico at Aguadilla

Period of support:

July 2022- June 2024

Title:

Role of glyoxylase in astrocytic supportive function under hyperglycemic conditions.

Goal:

Elucidate the role of the glyoxalase system on the supportive functions of astrocytes when grown in hyperglycemic conditions

Funding:

National institute of Health - National Institute of General Medicine

Total Cost:

$100,000

Role:

Principal Investigator

Managing Entity

Universidad Central del Caribe , School of Medicine

Period of support:

January 2018 - June 2021

Title:

Polyamines effect on C. elegance aging

Goal:

Determine the role of polyamines on C. elegance aging

Funding:

National Science Foundation

Total Cost:

$2,000

Role:

Undergraduate students’ mentor

Managing Entity

University of Puerto Rico at Aguadilla

Period of support:

August 2018 - May 2019

Title:

Diabetes and Astrocytes: impact on normal astrocyte function and its consequences.

Goal:

Identify a potential candidate that has a great possibility to explain the regulation of Kir4.1 potassium channel in astrocytes under high glucose conditions.

Funding:

National Institute of Health - National Institute of General Medicine

Total Cost:

$50,000

Role:

Consultant

Managing Entity

Universidad Central del Caribe , School of Medicine

Period of support:

July 2022 – June 2023

Title:

Interactive Neurophysiology Workshop to Promote Neuroscience Research in Undergraduate Colleges in Puerto Rico Project

Goal:

Provide a workshop that will provide software, equipment and laboratory exercises in the field of neurophysiology to faculty from UPR system.

Funding:

Grass Foundation

Total Cost:

$32,996

Role:

Co-Investigator

Managing Entity

University of Puerto Rico at Aguadilla

Period of support:

January 2021- December 2021

Title:

Polyamine depletion in C. elegance

Goal:

Study how the absence of polyamines will affect C. elegance to study other plant-parasitic nematodes that are part of a lot of the loses in agricultural goods.

Funding:

United Stated Department of Agriculture

Total Cost:

$700

Role:

Undergraduate students’ mentor

Managing Entity

University of Puerto Rico at Aguadilla

Period of support:

August 2018 - May 2019

Puerto Rico

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